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1

Synthesis of Aromatic 1,2-Amino Alcohols Utilizing a Bienzymatic Dynamic Kinetic Asymmetric Transformation

Johannes Steinreiber, Martin Schürmann, Friso van Assema, Michael Wolberg, Kateryna Fesko, Christoph Reisinger, Daniel Mink, Herfried Griengl

Journal:

Advanced Synthesis & Catalysis

Année:

2007

Langue:

english

Fichier:

PDF, 443 KB

english, 2007

2

Large-Scale Synthesis of New Pyranoid Building Blocks Based on Aldolase-Catalysed Carbon-Carbon Bond Formation

Michael Wolberg, Ben H. N. Dassen, Martin Schürmann, Stefan Jennewein, Marcel G. Wubbolts, Hans E. Schoemaker, Daniel Mink

Journal:

Advanced Synthesis & Catalysis

Année:

2008

Langue:

english

Fichier:

PDF, 249 KB

english, 2008

3

Overcoming Thermodynamic and Kinetic Limitations of Aldolase-Catalyzed Reactions by Applying Multienzymatic Dynamic Kinetic Asymmetric Transformations

Johannes Steinreiber, Martin Schürmann, Michael Wolberg, Friso van Assema, Christoph Reisinger, Kateryna Fesko, Daniel Mink, Herfried Griengl

Journal:

Angewandte Chemie International Edition

Année:

2007

Langue:

english

Fichier:

PDF, 110 KB

english, 2007

4

Threonine aldolases—an emerging tool for organic synthesis

Johannes Steinreiber, Kateryna Fesko, Christoph Reisinger, Martin Schürmann, Friso van Assema, Michael Wolberg, Daniel Mink, Herfried Griengl

Journal:

Année:

2007

Langue:

english

Fichier:

PDF, 296 KB

english, 2007

5

Chemoenzymatic synthesis of statine side chain building blocks and application in the total synthesis of the cholesterol-lowering compound solistatin

Rieder, Oliver, Wolberg, Michael, Foegen, Silke E., Müller, Michael

Journal:

Journal of Biotechnology

Année:

2017

Langue:

english

Fichier:

PDF, 356 KB

english, 2017

6

Highly Regio- and Enantioselective Reduction of 3,5-Dioxocarboxylates

Michael Wolberg, Werner Hummel, Christian Wandrey, Michael Müller

Journal:

Angewandte Chemie

Année:

2000

Langue:

english

Fichier:

PDF, 86 KB

english, 2000

7

Biocatalytic Reduction of β,δ-Diketo Esters: A Highly Stereoselective Approach to All Four Stereoisomers of a Chlorinated β,δ-Dihydroxy Hexanoate

Michael Wolberg, Werner Hummel, Michael Müller

Journal:

Chemistry - A European Journal

Année:

2001

Langue:

english

Fichier:

PDF, 188 KB

english, 2001

8

Asymmetric Total Synthesis of (−)-Callystatin A and (−)-20-epi-Callystatin A Employing Chemical and Biological Methods

Dieter Enders, Jose L. Vicario, Andreas Job, Michael Wolberg, Michael Müller

Journal:

Chemistry - A European Journal

Année:

2002

Langue:

english

Fichier:

PDF, 264 KB

english, 2002

9

Highly Regio- and Enantioselective Reduction of 3,5-Dioxocarboxylates

Michael Wolberg, Werner Hummel, Christian Wandrey, Michael Müller

Journal:

Angewandte Chemie International Edition

Année:

2000

Langue:

english

Fichier:

PDF, 86 KB

english, 2000

10

Überwindung der thermodynamischen und kinetischen Limitierungen Aldolase-katalysierter Reaktionen durch multienzymatische dynamische kinetische asymmetrische Umwandlungen

Johannes Steinreiber, Martin Schürmann, Michael Wolberg, Friso van Assema, Christoph Reisinger, Kateryna Fesko, Daniel Mink, Herfried Griengl

Journal:

Angewandte Chemie

Année:

2007

Langue:

german

Fichier:

PDF, 111 KB

german, 2007

11

ChemInform Abstract: Dynamic Kinetic Resolution of tert-Butyl 4-Methyl-3,5-dioxohexanoate Through Enzymatic Reduction.

Aiguo Ji, Michael Wolberg, Werner Hummel, Christian Wandrey, Michael Mueller

Journal:

Année:

2001

Fichier:

PDF, 27 KB

2001

12

ChemInform Abstract: Asymmetric Synthesis of S-(+)-Argentilactone (I) and S-(-)-Goniothalamin (II).

Andreas Job, Michael Wolberg, Michael Mueller, Dieter Enders

Journal:

Année:

2002

Fichier:

PDF, 25 KB

2002

13

ChemInform Abstract: Diastereomer-Differentiating Hydrolysis of 1,3-Diol-acetonides: A Simplified Procedure for the Separation of syn- and anti-1,3-Diols.

Silke E. Bode, Michael Mueller, Michael Wolberg

Journal:

Année:

2002

Fichier:

PDF, 29 KB

2002

14

ChemInform Abstract: Asymmetric Total Synthesis of (-)-Callystatin A Employing the SAMP/RAMP Hydrazone Alkylation Methodology.

Jose L. Vicario, Andreas Job, Michael Wolberg, Michael Mueller, Dieter Enders

Journal:

Année:

2002

Fichier:

PDF, 33 KB

2002

15

Asymmetric Total Synthesis of (-)-Callystatin A and (-)-20-epi-Callystatin A Employing Chemical and Biological Methods.

Dieter Enders, Jose L. Vicario, Andreas Job, Michael Wolberg, Michael Mueller

Journal:

Année:

2003

Langue:

english

Fichier:

PDF, 108 KB

english, 2003

16

Enzyme-Catalyzed Regio- and Enantioselective Ketone Reductions

Michael Mueller, Michael Wolberg, Thomas Schubert, Werner Hummel

Journal:

Année:

2005

Fichier:

PDF, 8 KB

2005

17

Radiation survival of human mammary carcinoma cells: Criteria for an agar-based clonogenic assay

Greta J. Besch, Martin A. Tanner, Carol A. Sattler, William H. Wolberg, Steven P. Howar, Michael N. Gould

Journal:

International Journal of Radiation Oncology*Biology*Physics

Année:

1986

Langue:

english

Fichier:

PDF, 880 KB

english, 1986

18

A comparison of methods for the production of monodispersed cell suspensions from human primary breast carcinomas

Greta J. Besch, William H. Wolberg, Kennedy W. Gilchrist, Joseph G. Voelkel, Michael N. Gould

Journal:

Breast Cancer Research and Treatment

Année:

1983

Langue:

english

Fichier:

PDF, 1.55 MB

english, 1983

19

Chemoenzymatic synthesis of the chiral side-chain of statins: application of an alcohol dehydrogenase catalysed ketone reduction on a large scale

Michael Wolberg, Murillo Villela Filho, Silke Bode, Petra Geilenkirchen, Ralf Feldmann, Andreas Liese, Werner Hummel, Michael Müller

Journal:

Bioprocess and Biosystems Engineering

Année:

2008

Langue:

english

Fichier:

PDF, 418 KB

english, 2008

20

Regio and enantioselective reduction of t-butyl 6-chloro-3,5-dioxohexanoate with baker’s yeast

Michael Wolberg, Iwona A. Kaluzna, Michael Müller, Jon D. Stewart

Journal:

Tetrahedron: Asymmetry

Année:

2004

Langue:

english

Fichier:

PDF, 261 KB

english, 2004

21

A core nucleosome surface crucial for transcriptional silencing

Park, Jeong-Hyun, Cosgrove, Michael S., Youngman, Elaine, Wolberger, Cynthia, Boeke, Jef D.

Journal:

Nature Genetics

Année:

2002

Langue:

english

Fichier:

PDF, 926 KB

english, 2002

22

Mms2–Ubc13 covalently bound to ubiquitin reveals the structural basis of linkage-specific polyubiquitin chain formation

Eddins, Michael J, Carlile, Candice M, Gomez, Kamila M, Pickart, Cecile M, Wolberger, Cynthia

Journal:

Nature Structural and Molecular Biology

Année:

2006

Langue:

english

Fichier:

PDF, 459 KB

english, 2006

23

Regulated nucleosome mobility and the histone code

Cosgrove, Michael S, Boeke, Jef D, Wolberger, Cynthia

Journal:

Nature Structural and Molecular Biology

Année:

2004

Langue:

english

Fichier:

PDF, 403 KB

english, 2004

24

Directed evolution of an industrial biocatalyst: 2-deoxy-D-ribose 5-phosphate aldolase

Stefan Jennewein, Martin Schürmann, Michael Wolberg, Iris Hilker, Ruud Luiten, Marcel Wubbolts, Daniel Mink

Journal:

Biotechnology Journal

Année:

2006

Langue:

english

Fichier:

PDF, 415 KB

english, 2006

25

Large-Scale Synthesis of the Glucosylceramide Synthase Inhibitor N-[5-(Adamantan-1-yl-methoxy)-pentyl]-1-deoxynojirimycin

Wennekes, Tom, Lang, Bernhard, Leeman, Michel, Marel, Gijsbert A. van der, Smits, Elly, Weber, Matthias, Wiltenburg, Jim van, Wolberg, Michael, Aerts, Johannes M.F.G., Overkleeft, Herman S.

Journal:

Organic Process Research & Development

Année:

2008

Langue:

english

Fichier:

PDF, 181 KB

english, 2008

26

NMR studies of the pbx1 TALE homeodomain protein free in solution and bound to DNA: proposal for a mechanism of HoxB1-pbx1-DNA complex assembly

Carole Jabet, Rossitza Gitti, Michael F Summers, Cynthia Wolberger

Journal:

Journal of Molecular Biology

Année:

1999

Langue:

english

Fichier:

PDF, 522 KB

english, 1999

27

Crystal Structure and Solution NMR Studies of Lys48-linked Tetraubiquitin at Neutral pH

Michael J. Eddins, Ranjani Varadan, David Fushman, Cecile M. Pickart, Cynthia Wolberger

Journal:

Journal of Molecular Biology

Année:

2007

Langue:

english

Fichier:

PDF, 1.16 MB

english, 2007

28

Recombinant factor VIIa analog NN1731 (V158D/E296V/M298Q-FVIIa) enhances fibrin formation, structure and stability in lipidated hemophilic plasma

Laura D. Gray, Michael A. Hussey, Brittany M. Larson, Kellie R. Machlus, Robert A. Campbell, Gary Koch, Mirella Ezban, Ulla Hedner, Alisa S. Wolberg

Journal:

Thrombosis Research

Année:

2011

Langue:

english

Fichier:

PDF, 922 KB

english, 2011

29

Structure of a HoxB1–Pbx1 Heterodimer Bound to DNA: Role of the Hexapeptide and a Fourth Homeodomain Helix in Complex Formation

Derek E. Piper, Adrian H. Batchelor, Ching-Pin Chang, Michael L. Cleary, Cynthia Wolberger

Journal:

Année:

1999

Langue:

english

Fichier:

PDF, 500 KB

english, 1999

30

Structure of a Sir2 Enzyme Bound to an Acetylated p53 Peptide

Jose L Avalos, Ivana Celic, Shabazz Muhammad, Michael S Cosgrove, Jef D Boeke, Cynthia Wolberger

Journal:

Année:

2002

Langue:

english

Fichier:

PDF, 1019 KB

english, 2002

31

The Structural Basis of Sirtuin Substrate Affinity †,‡

Cosgrove, Michael S., Bever, Katherine, Avalos, Jose L., Muhammad, Shabazz, Zhang, Xiangbin, Wolberger, Cynthia

Journal:

Année:

2006

Langue:

english

Fichier:

PDF, 664 KB

english, 2006

32

How does the histone code work?

Cosgrove, Michael S, Wolberger, Cynthia

Journal:

Biochemistry and Cell Biology

Année:

2005

Fichier:

PDF, 192 KB

2005

33

Diastereomer-Differentiating Hydrolysis of 1,3-Diol-Acetonides: A Simplified Procedure for the Separation of syn - and anti -1,3-Diols

Bode, Silke E., Müller, Michael, Wolberg, Michael

Journal:

Organic Letters

Année:

2002

Langue:

english

Fichier:

PDF, 45 KB

english, 2002

34

Asymmetric Total Synthesis of (−)-Callystatin A Employing the SAMP/RAMP Hydrazone Alkylation Methodology

Vicario, Jose L., Job, Andreas, Wolberg, Michael, Müller, Michael, Enders, Dieter

Journal:

Organic Letters

Année:

2002

Langue:

english

Fichier:

PDF, 59 KB

english, 2002

35

Dynamic kinetic resolution of tert-butyl 4-methyl-3,5-dioxohexanoate through enzymatic reduction

Ji, Aiguo, Wolberg, Michael, Wandrey, Christian, Müller, Michael, Hummel, Werner

Journal:

Chemical Communications

Année:

2001

Langue:

english

Fichier:

PDF, 56 KB

english, 2001

36

Antiproliferative Effects of Interferons on Human Melanoma Cells in the Human Tumor Colony-Forming Assay

SCHILLER, JOAN H., WILLSON, JAMES K.V., BITTNER, GERARD, WOLBERG, WILLIAM H., HAWKINS, MICHAEL J., BORDEN, ERNEST C.

Journal:

Journal of Interferon Research

Année:

1986

Langue:

english

Fichier:

PDF, 1.16 MB

english, 1986

37

E2 ubiquitin-conjugating enzymes regulate the deubiquitinating activity of OTUB1

Wiener, Reuven, DiBello, Anthony T, Lombardi, Patrick M, Guzzo, Catherine M, Zhang, Xiangbin, Matunis, Michael J, Wolberger, Cynthia

Journal:

Nature Structural and Molecular Biology

Année:

2013

Langue:

english

Fichier:

PDF, 1.03 MB

english, 2013

38

Asymmetric Synthesis of S-(+)-Argentilactone and S-(-)-Goniothalamin

Job, Andreas, Wolberg, Michael, Müller, Michael, Enders, Dieter

Journal:

Année:

2001

Langue:

english

Fichier:

PDF, 75 KB

english, 2001

39

Enzymatic Reduction of Hydrophobic β,δ-Diketo Esters

Wolberg, Michael, Ji, Aiguo, Hummel, Werner, Müller, Michael

Journal:

Année:

2001

Langue:

english

Fichier:

PDF, 123 KB

english, 2001

40

Stereoselective Synthesis of 1,3-Diols

Bode, Silke E., Wolberg, Michael, Müller, Michael

Journal:

Année:

2006

Langue:

english

Fichier:

PDF, 618 KB

english, 2006

41

Multifunctional β-NaGdF 4 :Ln 3+ (Ln = Yb, Er, Dy) nanoparticles with NIR to visible upconversion and high transverse relaxivity: a potential bimodal contrast agent for high-field MRI and optical imaging

Biju, Silvanose, Harris, Michael, Elst, Luce Vander, Wolberg, Marike, Kirschhock, Christine, Parac-Vogt, Tatjana N.

Journal:

Année:

2016

Langue:

english

Fichier:

PDF, 664 KB

english, 2016

42

Chemical Synthesis of Phosphorylated Histone H2A at Tyr57 Reveals Insight into the Inhibition Mode of the SAGA Deubiquitinating Module

Jbara, Muhammad, Maity, Suman Kumar, Morgan, Michael, Wolberger, Cynthia, Brik, Ashraf

Journal:

Angewandte Chemie

Année:

2016

Langue:

english

Fichier:

PDF, 1.82 MB

english, 2016

43

Chemical Synthesis of Phosphorylated Histone H2A at Tyr57 Reveals Insight into the Inhibition Mode of the SAGA Deubiquitinating Module

Jbara, Muhammad, Maity, Suman Kumar, Morgan, Michael, Wolberger, Cynthia, Brik, Ashraf

Journal:

Angewandte Chemie International Edition

Année:

2016

Langue:

english

Fichier:

PDF, 1.86 MB

english, 2016

44

LYMPHOCYTE REACTIVITY IN VITRO

Bach, Marilyn L., Bach, Fritz H., Widmer, Michael, Oranen, Helena, Wolberg, William H.

Journal:

Transplantation Journal

Année:

1971

Fichier:

PDF, 245 KB

1971

45

Recognition of ubiquitinated nucleosomes

Morgan, Michael T, Wolberger, Cynthia

Journal:

Current Opinion in Structural Biology

Année:

2017

Langue:

english

Fichier:

PDF, 2.15 MB

english, 2017

46

RAP80, ubiquitin and SUMO in the DNA damage response

Lombardi, Patrick M., Matunis, Michael J., Wolberger, Cynthia

Journal:

Journal of Molecular Medicine

Année:

2017

Langue:

english

Fichier:

PDF, 2.98 MB

english, 2017

47

Genome Wide Measurements of the Sequence Dependence of Nucleosomal DNA Flexibility

Basu, Aakash, Morgan, Michael T., Huaman, Basilio C., Kayikcioglu, Tunc, Ngo, Thuy, Zhang, Qiucen, Wolberger, Cynthia, Ha, Taekjip

Journal:

Biophysical Journal

Année:

2018

Langue:

english

Fichier:

PDF, 44 KB

english, 2018

48

Hydrazide Mimics for Protein Lysine Acylation to Assess Nucleosome Dynamics and Deubiquitinase Action

Bhat, Shridhar, Hwang, Yousang, Gibson, Matthew D, Morgan, Michael T, Taverna, Sean D., Zhao, Yingming, Wolberger, Cynthia, Poirier, Michael Guy, Cole, Philip A

Journal:

Journal of the American Chemical Society

Année:

2018

Langue:

english

Fichier:

PDF, 2.19 MB

english, 2018

49

State of the art in factor XIII laboratory assessment

Durda, Michael A., Wolberg, Alisa S., Kerlin, Bryce A.

Journal:

Transfusion and Apheresis Science

Année:

2018

Fichier:

PDF, 550 KB

2018

50

Palladium prompted on-demand cysteine chemistry for the synthesis of challenging and uniquely modified proteins

Jbara, Muhammad, Laps, Shay, Morgan, Michael, Kamnesky, Guy, Mann, Guy, Wolberger, Cynthia, Brik, Ashraf

Journal:

Nature Communications

Année:

2018

Langue:

english

Fichier:

PDF, 2.06 MB

english, 2018